ABD 3e Interleaf 7 (p. 368)
Select an appropriate statistical test for a given research question and dataset
Use information about variables, study design, and number of groups to guide test selection
Evaluate whether the assumptions of a chosen method are reasonable
Apply a logical sequence of questions (a mental flow chart) to choose a test
Very common situation: you have a question, you collected data, but now you don’t know what test to use to answer the question.
The following tables lay out your options.
In the future, you should be able to apply this thinking to your own research.
For now, you should be able to read an example of a question and data set and decide which test is appropriate.
For examples of questions, see the Practice and Assignment problems at the end of each chapter.
Now imagine you read a question but didn’t know which chapter it came from. Could you choose the appropriate statistical procedure to answer the question?
| Goal | Test |
|---|---|
| Use frequency data to test whether a population proportion equals a null hypothesized value | Binomial test (Lecture 9) \(\chi^2\) goodness-of-fit test with two categories (use if sample size is too large for the binomial test) (Lecture 10) |
| Use frequency data to test the fit of a specific population model | \(\chi^2\) goodness-of-fit test (Lecture 10) |
| Goal | Test |
|---|---|
| Test whether the mean equals a null hypothesized value when data are approximately normal (possibly only after a transformation) (13) | One-sample \(t\)-test (Lecture 14) |
| Test whether the median equals a null hypothesized value when data are not normal (even after transformation) | Sign test (Lecture 16) |
| Use frequency data to test the fit of a discrete probability distribution | \(\chi^2\) goodness-of-fit test (Lecture 11) |
| Use data to test the fit of the normal distribution | Shapiro-Wilk test (Lecture 16) |
| Type of Explanatory Variable | |||
| Ca tegorical | Numerical | ||
| Type of Response Variable | Ca tegorical | Contingency analysis (Lecture 12) | Logistic Regression (Lecture 23) |
| Numerical | See next slide | Linear Correlation (Lecture 21) and Spearman’s rank correlation (when data are not bivariate normal) (Lecture 21) Linear regression (Lecture 22) and nonlinear regression (Lecture 23) |
| Number of treatments | Tests assuming normal distribution | Fewer assumptions (do not require normality) |
|---|---|---|
| Two treatments (independent samples) | Pooled variance two-sample \(t\)-test (Lecture 15) (assumes equal variances, not commonly used) Welch’s two-sample \(t\)-test (Lecture 15) (Preferred when variances are unequal (often the default in practice) |
Wilcoxon Rank-Sum Test (Mann-Whitney \(U\)-test) (Lecture 16) |
| Two treatments (paired samples) | Paired \(t\)-test (Lecture 15) | Sign test (Lecture 16) |
| More than two treatments | ANOVA (Lecture 20) | Kruskal-Wallis test (Lecture 20) |
This is what you need to know for this course, but it is not a comprehensive list of hypothesis tests
Some other resources:
What statistical test should I do? Stats and R
Quantitative Analysis Guide, NYU Libraries
Statistical method selection tool, Statkat

BIOL 275 Biostatistics | Spring 2026